NASA Case Study Essay Example | Topics and Well Written Essays - 500 words

NASA Case Study - Essay Example Even without physical examination, a break on the tubing means an inappropriate strength of materials used, as it was not able to withstand the pressure. One could quickly suggest poor estimation, poor quality of materials, and the aircraft mechanics were not really proficient or experts, or simply that the material engineers and management were simply experimenting on strength of materials having taken the risk. In the first place, before the materials were used it should have been accurately tried and tested to efficiently serve the function from launch time to the time when the spacecraft could have safely landed back on its pad on earth Definitely, the tragedy of Columbia Space Shuttle in 2003 was a learning lesson for the National Aeronautics Space Administration. But, it could have been prevented. Obviously, minor problems should be given the highest attention for resolution. This means that considering the extreme risk of a space travel by a space craft, no single edge of flaw should be tolerated. In other words, there should be a zero flaw on space shuttle structure and function. Moreover, a spacecraft should not have been attempted launched even for a single or minor imperfection. A completed checklist on parts and function should have been confirmed and reconfirmed by the experts to get a 101% assurance of perfection before set off. There should be ‘no rock left unturned’. Otherwise, there should be no room or space for ambiguity because everything can be calculated closest to precision considering previous projects of similar nature and the perspectives gained by the organizational manpower. In reality, the tragedy should not have happened (Roberto et al, 2006). Gross negligence is a real management problem and not simple ambiguity. This is because this is a scientific undertaking which follows protocol scientific pattern of doing things. Extensive

COLOURIMETRY PARACETAMOL Essay Example | Topics and Well Written Essays - 1000 words

COLOURIMETRY PARACETAMOL - Essay Example Colourimetry is an extremely useful technique in establishing the concentration of substances. This is achieved by preparing a known concentration series of about 4 solutions, after which their absorbance is determined after the addition of colour by a reagent. The absorbance values give a calibration curve from which the concentration of an unknown substance is established. This technique is useful in the determination of metal ions alloys and biological fluids. Numerous industrial and clinical experiments report the successful usage of colorimetric procedures in the establishment of the concentrations of chemical substances. For example, the determination of vitamin E in food, trace amounts of platinum in glass, flavonoids in food, and detection of alpha fetoproteins among many other uses. Paracetamol (4-acetamedophenol) is a commonly used painkiller that lessens the temperature of fever patients. Its pain reducing effects are known as analgesic effects whereas its fever reduction action is called the antipyretic effect. Numerous over the counter medications contain paracetamol especially those meant for the relief of colds and flu. The most common form is the 500 mg tablet though other formulations such as suspensions and suppositories also exist. Paracetamol is quickly taken in from the gastrointestinal tract and attains peak plasma concentrations in about an hour. The cytochrome P450 system metabolises it into N-acetyl-p-benzoquinamine (NAPQI), a toxin that is entirely detoxified through conjugation with glutathione and excreted. Paracetamol is a fairly safe drug. However, doses greater than 10 grams have been reported to cause toxicity (Bose et al. 2005). This experiment aimed at using colourimetry as a chemical technique to make a calibration curve of absorbance a gainst concentration for known paracetamol concentrations and using it to obtain the concentration of paracetamol in the sample with the unknown concentration. Materials and Method 100 ml of 0.002M paracetamol solution was prepared by dissolving the right quantity of the drug in 10 ml of sodium chloride solution and topping up to 100 ml. This was the stock solution for the experiment. 1.0 ml of 6M HCl and 2 ml of 10% sodium nitrite were added to each of the seven labelled test tubes. Paracetamol and water were then added to the tubes in predetermined quantities after which the tubes were methodically mixed and allowed to rest for about 2 minutes. 2 ml of 15% sodium sulphamate were carefully added to the test tubes followed by 2.5 ml of 25% sodium hydroxide. The tubes were shaken for 15 seconds and allowed to stand for 2 minutes. This allowed all the bubbles to disperse. The absorbance of the contents of tubes 2 to 7 was then read at a wavelength of 430 nanometers using tube 1 as the blank. The values of absorbance were recorded for each concentration of paracetamol. A calibration graph of absorbance against concentration (mol/L) was then plotted and used to approximate the concentration